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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5354 |
IRAK4-IN-7
CA-4948 |
IRAK | Immunology/Inflammation; NF-κB |
IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂,口服有活性。它可用于研究癌症以及炎症疾病。 | |||
T4140 |
IRAK4-IN-1
|
IRAK | Immunology/Inflammation; NF-κB |
IRAK4-IN-1 是白细胞介素-1 受体相关激酶 4 抑制剂(IC50:7 nM)。 | |||
T77171 |
Efineptakin alfa
|
||
Efineptakin alfa (NT-17) 是一种长效重组人 IL-7。 Efineptakin alfa 支持人和小鼠体内 CD4+和 CD8+细胞的增殖和存活。 Efineptakin alfa 可用于胶质母细胞瘤的研究。 | |||
T82060 |
Interleukin-6 fragment (human)
|
||
Interleukin-6 fragment (human) 是一种多效性细胞因子,由淋巴细胞及非淋巴细胞产生。该分子的编码基因位于人类第7号染色体,长度大约为5 kb。Interleukin-6 fragment (human) 在免疫响应、急性相应、炎症过程、癌症治疗及血液造血方面均有重要的潜在应用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2S0843 |
Negletein
黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether |
IL Receptor; TNF; NOS; Interleukin | Apoptosis; Immunology/Inflammation |
Negletein (7-O-Methylbaicalein) 一种神经保护剂,可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性,其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。 | |||
TN1291 |
7,3',4'-Tri-O-methylluteolin
5-Hydroxy-3',4',7-trimethoxyflavone,木犀草素-7,3',4'-三甲醚 |
TNF; COX; Interleukin | Apoptosis; Immunology/Inflammation; Neuroscience |
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) 是来自草药马鞭草科的一种类黄酮,具有抗炎,解热,镇咳,抗糖尿病、抗癌和抗黑素生成特性。它以浓度依赖方式明显抑制促炎细胞因子,可显著降低在转录水平的诱导型一氧化氮合酶和环加氧酶-2 的 mRNA 表达。 | |||
T7786 |
Tryptanthrin
|
DNA gyrase | DNA Damage/DNA Repair |
Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。 它能够降低大鼠胸膜炎模型中的 LTB4 水平,并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03383 |
IL-7 Protein, Human, Recombinant
IL-7,interleukin 7,Interleuki... |
Human | E. coli |
IL-7 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P13232-1. | |||
TMPY-00635 |
IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)
IL7R α/CD127,interleukin 7 |
Cynomolgus | HEK293 Cells |
IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is Q38IC7. | |||
TMPJ-00038 |
IL-7 Protein, Mouse, Recombinant (His)
interleukin-7,白介素,IL-7,IL-7 |
Mouse | HEK293 Cells |
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell... | |||
TMPY-00524 |
IL-7 Protein, Mouse, Recombinant
Il-7,A630026I06Rik,interleukin 7,... |
Mouse | E. coli |
IL-7 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is P10168. | |||
TMPJ-00059 |
IL-7 Protein, Human, Recombinant (His)
Interleukin-7,IL7,白细胞介素,IL-7<... |
Human | HEK293 Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-spe... | |||
TMPY-01209 |
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
IL7RA,ILRA,CD127,CDW127,IL-7<... |
Human | HEK293 Cells |
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1. | |||
TMPY-02087 |
IL-24 Protein, Human, Recombinant (His)
C49A,IL10B,MOB5,ST16,MDA7,FISP,interleukin... |
Human | HEK293 Cells |
IL-24 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is A0A7R8C2Y5. | |||
TMPY-01446 |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
IL-18Rbeta,CD218b,IL-18R β/IL-18RAP,IL-18Rβ,ACPL,IL-18R-beta... |
Human | HEK293 Cells |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1. | |||
TMPY-03154 |
IL-7R alpha/CD127 Protein, Rat, Recombinant (mFc)
IL7R α/CD127,interleukin 7 |
Rat | HEK293 Cells |
IL-7R alpha/CD127 Protein, Rat, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.4 kDa and the accession number is D4A3X8. | |||
TMPY-03730 |
IL-7R alpha/CD127 Protein, Rat, Recombinant (His)
interleukin 7 receptor,IL7R α/CD1... |
Rat | HEK293 Cells |
IL-7R alpha/CD127 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is A6KGJ9. | |||
TMPY-04042 |
IL-7 Protein, Rat, Recombinant
interleukin 7,白细胞介素,白介素 |
Rat | E. coli |
IL-7 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q91Y32. | |||
TMPY-01367 |
IL-7R alpha/CD127 Protein, Mouse, Recombinant (His)
IL7R α/CD127,interleukin 7 |
Mouse | HEK293 Cells |
IL-7R alpha/CD127 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16872. | |||
TMPJ-00285 |
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His)
CD127,IL-7R-alpha,IL-7R-α,Int... |
Human | HEK293 Cells |
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His) is ... | |||
TMPY-00400 |
IL-17B Protein, Human, Recombinant (hFc)
ZCYTO7,IL-20,IL-17B,NIRF,interleukin |
Human | Baculovirus Insect Cells |
IL-17B Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is Q9UHF5. | |||
TMPJ-00344 |
IL-18RAP Protein, Human, Recombinant (hFc & His)
IL-1R accessory protein-like,Interleukin-18 recepto... |
Human | HEK293 Cells |
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease. | |||
TMPK-00060 |
IL-17B Protein, Mouse, Recombinant (His)
IL20,interleukin 17B,interleukin ... |
Mouse | E. coli |
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/IL-17RB expression patterns and biological activities in cancer and highlight issues that remain to be addressed to better characterize IL-17B and its receptor as potential targets for enhancing the effectiveness of the existing cancer therapies. | |||
TMPJ-00284 |
IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
Interleukin-7 receptor subunit alpha,IL- |
Mouse | HEK293 Cells |
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expres... | |||
TMPY-05377 |
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc)
ILRA,interleukin 7 receptor,IL7R ... |
Human | HEK293 Cells |
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is P16871-1. | |||
TMPY-06580 |
IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated
IL7R α/CD127,ILRA,CD127,IL-7<... |
Human | HEK293 Cells |
IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.14 kDa and the accession number is P16871-1. | |||
TMPY-05177 |
IL-24 Protein, Human, Recombinant (mFc)
白细胞介素,ST16,interleukin 24,白介素,MDA7,IL10B,C... |
Human | HEK293 Cells |
IL-24 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 44.6 kDa and the accession number is A0A7R8C2Y5. | |||
TMPY-06316 |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated
IL-18Rbeta,IL-18R β/IL-18RAP,IL-1R7,IL18RB,IL-18RAc... |
Human | HEK293 Cells |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.04 kDa and the accession number is NP_003844.1. | |||
TMPY-01200 |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)
IL-1R-7,IL-1R7,interleukin 18 rec... |
Human | HEK293 Cells |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is O95256-1. | |||
TMPY-06312 |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated
ACPL,CDw218b,IL-18RAcP,IL-18R-β,IL-1R-7,IL-1RAcPL,C... |
Human | HEK293 Cells |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.76 kDa and the accession number is NP_003844.1. | |||
TMPJ-00042 |
TSLP Protein, Human, Recombinant
TSLP,Thymic stromal lymphopoietin |
Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral... | |||
TMPK-01331 |
TSLPR Protein, Cynomolgus, Recombinant (His)
CRL2,CRLF2,IL-XR,CRLF2Y,p2RY8/CRLF2 fusion,TSLPR,TSLP recept... |
Cynomolgus | HEK293 Cells |
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2). | |||
TMPY-06036 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7. | |||
TMPY-02597 |
IL-37 Protein, Human, Recombinant
FIL1Z,IL-37,白细胞介素,IL37,IL1F7,IL-1... |
Human | E. coli |
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression i... | |||
TMPJ-00177 |
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
BAFF,Dendritic cell-derived TNF-like molecule,CD257... |
Human | HEK293 Cells |
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymor... | |||
TMPJ-00239 |
IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)
Il2rg,Interleukin 2 receptor, gamma chain, isoform ... |
Mouse | HEK293 Cells |
The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15.... | |||
TMPY-02549 |
GBP1 Protein, Human, Recombinant (His)
guanylate binding protein 1,GBP1 |
Human | HEK293 Cells |
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secre... | |||
TMPY-02246 |
HB-EGF Protein, Human, Recombinant
DTSF,DTR,HEGFL,heparin-binding EGF-like growth factor,DTS |
Human | Baculovirus Insect Cells |
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of... | |||
TMPK-00828 |
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin-1,H23AG,PEM,CA 15... |
Human | HEK293 Cells |
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. | |||
TMPK-00392 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1 |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb... | |||
TMPK-00394 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1 |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ... | |||
TMPK-01371 |
IGFBP-7 Protein, Human, Recombinant (hFc)
RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7 |
Human | HEK293 Cells |
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres... | |||
TMPK-00395 |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGF R1a,FGFR1 α,FGFR1 alpha,FGFR1 α (IIIc) |
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7. | |||
TMPK-00393 |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 α,FGFR1 alpha,FGF R1a,FGFR1 α (IIIc) |
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7. | |||
TMPY-06035 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR,HBGFR,FLT-2,FGFB... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7. |